SHOCK?: Injury, Inflammation, and Sepsis: Laboratory and Clinical Approaches includes studies of novel therapeutic approaches, such as immunomodulation, gene therapy, nutrition, and others. The mission of the Journal is to foster and promote multidisciplinary studies, both experimental and clinical in nature, that critically examine the etiology, mechanisms and novel therapeutics of shock-related pathophysiological conditions. Its purpose is to excel as a vehicle for timely publication in the areas of basic and clinical studies of shock, trauma, sepsis, inflammation, ischemia, and related pathobiological states, with particular emphasis on the biologic mechanisms that determine the response to such injury. Making such information available will ultimately facilitate improved care of the traumatized or septic individual.

《Shock》是一本由LIPPINCOTT WILLIAMS & WILKINS出版商出版的专业医学期刊，该刊创刊于1994年，刊期Monthly，该刊已被国际权威数据库SCI、SCIE收录。在中科院最新升级版分区表中，该刊分区信息为大类学科：医学 3区，小类学科：血液学 3区；外周血管病 3区；外科 3区；危重病医学 4区；在JCR（Journal Citation Reports）分区等级为Q2。该刊发文范围涵盖危重病医学等领域，旨在及时、准确、全面地报道国内外危重病医学工作者在该领域取得的最新研究成果、工作进展及学术动态、技术革新等，促进学术交流，鼓励学术创新。2021年影响因子为3.533，平均审稿速度约1.0个月。