Microbiology Spectrum publishes commissioned review articles on topics in microbiology representing ten content areas: Archaea; Food Microbiology; Bacterial Genetics, Cell Biology, and Physiology; Clinical Microbiology; Environmental Microbiology and Ecology; Eukaryotic Microbes; Genomics, Computational, and Synthetic Microbiology; Immunology; Pathogenesis; and Virology. Reviews are interrelated, with each review linking to other related content. A large board of Microbiology Spectrum editors aids in the development of topics for potential reviews and in the identification of an editor, or editors, who shepherd each collection.

《Microbiology Spectrum》是一本由AMER SOC MICROBIOLOGY出版商出版的专业生物期刊，该刊创刊于2013年，刊期6 issues/year，该刊已被国际权威数据库SCIE收录。在中科院最新升级版分区表中，该刊分区信息为大类学科：生物 2区，小类学科：微生物学 2区；在JCR（Journal Citation Reports）分区等级为Q1。该刊发文范围涵盖微生物学等领域，旨在及时、准确、全面地报道国内外微生物学工作者在该领域取得的最新研究成果、工作进展及学术动态、技术革新等，促进学术交流，鼓励学术创新。2021年影响因子为9.043，