Genome Biology?covers all areas of biology and biomedicine studied from a genomic and post-genomic perspective. Content includes research, new methods and software tools, and reviews, opinions and commentaries. Areas covered include, but are not limited to: sequence analysis; bioinformatics; insights into molecular, cellular and organismal biology; functional genomics; epigenomics; population genomics; proteomics; comparative biology and evolution; systems and network biology; genome editing and engineering; genomics of disease; and clinical genomics.

《Genome Biology》是一本由BMC出版商出版的专业生物期刊，该刊创刊于2000年，刊期Monthly，该刊已被国际权威数据库SCIE收录。在中科院最新升级版分区表中，该刊分区信息为大类学科：生物学 1区，小类学科：生物工程与应用微生物 1区；遗传学 1区；在JCR（Journal Citation Reports）分区等级为Q1。该刊发文范围涵盖生物工程与应用微生物等领域，旨在及时、准确、全面地报道国内外生物工程与应用微生物工作者在该领域取得的最新研究成果、工作进展及学术动态、技术革新等，促进学术交流，鼓励学术创新。2021年影响因子为17.906，平均审稿速度14 Weeks。