Cell Chemical Biology is a Cell Press journal publishing research and review content of exceptional interest for the chemical biology community. Launched in 1994 under the title Chemistry & Biology, the journal was the first to recognize the growing importance of investigations done at the interface of chemistry and biology, and its mission has always been to support and promote chemical biology and conversation and collaboration between chemical and life sciences.

Cell Chemical Biology strongly encourages submission of articles that provide significant conceptual advancement of broad general interest to both chemists and biologists. We are especially interested in papers that combine the use of chemical tools to perturb, visualize, and measure biological systems and properties and offer unique insights into molecular mechanism or physiology. We also encourage submissions that are focused on method development for basic life sciences or that have practical impact of either clinical or biotechnological nature. Some additional types of research that we consider within our scope are studies of metabolism and physiology; enzyme mechanism and natural product biosynthesis; generation, distribution, and function of small molecule-protein conjugates such as post-translational modifications; mechanism of resistance to small molecules by viruses/bacteria/cancer cells/organisms; intra- and intercellular and intra- and interspecies communication mediated by small molecules; and chemical biology of lipids, sugars, and nucleic acids. Finally, large-scale studies enabled by the use of chemistry-based technology, such as proteomics, lipidomics, metabolomics, and glycomics, are also within our scope, as well as synthetic and systems biology work when inspired and supported by chemical tools or aimed at engineering biological systems to perform a new type of chemical transformation.

《Cell Chemical Biology》是一本由CELL PRESS出版商出版的专业生物期刊，该刊创刊于1994年，刊期12 issues/year，该刊已被国际权威数据库SCI、SCIE收录。在中科院最新升级版分区表中，该刊分区信息为大类学科：生物 2区，小类学科：生化与分子生物学 2区；在JCR（Journal Citation Reports）分区等级为Q1。该刊发文范围涵盖生化与分子生物学等领域，旨在及时、准确、全面地报道国内外生化与分子生物学工作者在该领域取得的最新研究成果、工作进展及学术动态、技术革新等，促进学术交流，鼓励学术创新。2021年影响因子为9.039，